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It includes The Element of Crime (1984), Epidemic (1987), and Europa (1991). Trier completed the Europa trilogy in 1991 with Europa (released as Zentropa in the US), which won the Prix du their most recent film at the time, Zentropa has produced many movies other than Trier's own, as well as several television series.
Von Trier directed Medea (1988) for television, which won him the Jean d'Arcy prize in France. It has also produced hardcore sex films: Constance (1998), Pink Prison (1999), Hot Men Cool Boyz (2000), and All About Anna (2005).
The producer doesn't like the short twelve-page script, which has no violence, few deaths, and no subplots (which are common in Danish cinema).
After the trip, Niels goes to a hospital where he undergoes a minor surgical procedure and while there tells Lars to go to see Palle, a pathologist who is performing an autopsy on a man who has recently died of an unknown disease.
The last day, Lars and Niels have a dinner with their producer, to whom they reveal the end of the film, that Mesmer and his medical kit have spread the disease.
Both films had casts of major international actors including Harriet Andersson, Lauren Bacall, James Caan, Danny Glover, Willem Dafoe, and questioned various issues relating to American society, such as intolerance (in Dogville) and slavery (in Manderlay).
The US was also the scene for Dear Wendy (2005), a feature film directed by von Trier.
During the next days, the facts of the script join the real-life events in which a similar disease starts to spread.